Flapless Cone Beam Computed Tomography-Guided Implant Surgery with Contextual Transcrestal Sinus Lift Augmentation Using New Bone Compactor Tools

In the present paper, the authors present a case report of premolar edentulism in the upper jaw treated through a guided flapless oral implant surgery with contextual crestal sinus lift, performed with a system of manual screw-tapered bone expanders (B&B Dental, San Benedetto, BO, Italy). The surgery was planned by means of dedicated software, through which the data obtained from the CBCT and from intraoral scanner impression were matched, with consequent production of a surgical template. The proposed surgical procedure is minimally invasive, very simple, and fast and ensures good comfort for the patient by avoiding the elevation of mucoperiosteal flaps and uncomfortable malleting maneuvers. In addition, the presented method shows a good degree of correspondence between the ideal position of the implant in the planning phase and the actual one detectable after the surgery

Multi instanton tests of holography

Gauge theories living on stacks of D7-branes are holographically related to IIB gravitational backgrounds with a varying axion-dilaton field (F-theory). The axion-dilaton field is generated by D7, O7 and D-instanton sources and can be written in terms of the chiral correlators of the eight dimensional gauge theory living on the D7-branes. Using localization techniques, we prove that the same correlators determine the gauge coupling of the four-dimensional N=2 supersymmetric SU(2) gauge theories living on the elementary D3-brane which probes the F-theory geometries.Comment: 18 page

Use of dermal-fat grafts in the post-oncological reconstructive surgery of atrophies in the zygomatic region: Clinical evaluations in the patients undergone to previous radiation therapy

Introduction: Grafting of autologous adipose tissue can be recommended in some cases of facial plastic surgery. Rhabdomyosarcoma is a type of cancer that can also affect the orbit. Enucleation of the eye can cause atrophy of the corresponding hemiface and decreased orbital growth.Case report: We report a case of a female patient with a medical history of surgical enucleation of the right eyeball, who had received rhabdomyosarcoma radiation therapy in her youth. The patient presented with a depression in the right zygomatic region. We took a dermal-fat flap from the abdominal region, which had been previously treated.Results: The surgical outcome, 48 hours, and much clearly 31 days after the surgery, revealed that the right zygomatic region had returned to its proper anatomical shape, although there were still signs of postoperative edema.Discussion: Very damaged tissues, like those exposed to radiation therapy, are generally not suitable for grafting of adipose tissue.Conclusions: In the described case, we achieved a technically and aesthetically satisfying result despite the patient's medical history involving several perplexities about the use of autologous dermal-fat tissues, because of prior radiation therapy exposure. The clinical case shows that even a region exposed to radiation therapy can be a valid receiving bed for dermal-fat grafting. © 2012 Inchingolo et al.; licensee BioMed Central Ltd

Modular anomaly equations in N N \mathcal{N} =2* theories and their large-N limit

We propose a modular anomaly equation for the prepotential of the N=2* super Yang-Mills theory on R^4 with gauge group U(N) in the presence of an Omega-background. We then study the behaviour of the prepotential in a large-N limit, in which N goes to infinity with the gauge coupling constant kept fixed. In this regime instantons are not suppressed. We focus on two representative choices of gauge theory vacua, where the vacuum expectation values of the scalar fields are distributed either homogeneously or according to the Wigner semi-circle law. In both cases we derive an all-instanton exact formula for the prepotential. As an application, we show that the gauge theory partition function on S^4 at large N localises around a Wigner distribution for the vacuum expectation values leading to a very simple expression in which the instanton contribution becomes independent of the coupling constant

The impact of vegan diet in the prevention and treatment of type 2 diabetes: A systematic review

A protective effect of vegan diets on health outcomes has been observed in previous studies, but its impact on diabetes is still debated. The aim of this review is to assess the relationship between vegan diets and the risk for type 2 diabetes (T2D) along with its effect on glycemic control and diabetes-related complications. In accordance with PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines, Pubmed and Cochrane library databases were systematically searched for all relevant studies. Seven observational and eight randomized controlled (RCTs) studies were included. The methodological quality of studies was assessed using the National Institutes of Health quality assessment tool for observational cohort and cross-sectional studies and the Cochrane Risk of Bias Tool for RCTs. We found that a vegan diet is associated with lower T2D prevalence or incidence and in T2D patients decreases high glucose values and improves glucose homeostasis, as reported from the majority of included studies. This approach seems to be comparable to other recommended healthful eating models, but as it may have potential adverse effects associated with the long-term exclusion of some nutrients, appropriate nutritional planning and surveillance are recommended, particularly in specific groups of diabetic patients such as frail elderly, adolescents, and pregnant or breastfeeding women

Challenges and Opportunities of Multimodality and Data Fusion in Remote Sensing

International audience—Remote sensing is one of the most common ways to extract relevant information about the Earth and our environment. Remote sensing acquisitions can be done by both active (synthetic aperture radar, LiDAR) and passive (optical and thermal range, multispectral and hyperspectral) devices. According to the sensor, a variety of information about the Earth's surface can be obtained. The data acquired by these sensors can provide information about the structure (optical, synthetic aperture radar), elevation (LiDAR) and material content (multi and hyperspectral) of the objects in the image. Once considered together their comple-mentarity can be helpful for characterizing land use (urban analysis, precision agriculture), damage detection (e.g., in natural disasters such as floods, hurricanes, earthquakes, oil-spills in seas), and give insights to potential exploitation of resources (oil fields, minerals). In addition, repeated acquisitions of a scene at different times allows one to monitor natural resources and environmental variables (vegetation phenology, snow cover), anthropological effects (urban sprawl, deforestation), climate changes (desertification, coastal erosion) among others. In this paper, we sketch the current opportunities and challenges related to the exploitation of multimodal data for Earth observation. This is done by leveraging the outcomes of the Data Fusion contests, organized by the IEEE Geoscience and Remote Sensing Society since 2006. We will report on the outcomes of these contests, presenting the multimodal sets of data made available to the community each year, the targeted applications and an analysis of the submitted methods and results: How was multimodality considered and integrated in the processing chain? What were the improvements/new opportunities offered by the fusion? What were the objectives to be addressed and the reported solutions? And from this, what will be the next challenges

Dietary and protective factors to halt or mitigate progression of autoimmunity, covid-19 and its associated metabolic diseases

COVID-19 is without any doubt the worst pandemic we have faced since the H1N1 virus outbreak. Even if vaccination against SARS-CoV-2 infection is becoming increasingly available, a more feasible approach for COVID-19 prevention and therapy is still needed. Evidence of a pathological link between metabolic diseases and severe forms of COVID-19 has stimulated critical reflection and new considerations. In particular, an abnormal immune response observed in certain patients with SARS-CoV-2 infection suggested possible common predisposing risk factors with autoimmune diseases such as Type 1 Diabetes (T1D). Correct supplementation with dietary factors may be key to preventing and counteracting both the underlying metabolic impairment and the complications of COVID-19. A set of agents may inhibit the cytokine storm and hypercoagulability that characterize severe COVID-19 infection: vitamin D3, omega-3 polyunsaturated fatty acids, polyphenols like pterostilbene, polydatin and honokiol, which can activate anti-inflammatory and antioxidant sirtuins pathways, quercetin, vitamin C, zinc, melatonin, lactoferrin and glutathione. These agents could be highly beneficial for subjects who have altered immune responses. In this review, we discuss the antiviral and metabolic effects of these dietary factors and propose their combination for potential applications in the prevention and treatment of COVID-19. Rigorous studies will be fundamental for validating preventive and therapeutic protocols that could be of assistance to mitigate disease progression following SARS-CoV-2 infection

z~2: An Epoch of Disk Assembly

We explore the evolution of the internal gas kinematics of star-forming galaxies from the peak of cosmic star-formation at $z\sim2$ to today. Measurements of galaxy rotation velocity $V_{rot}$, which quantify ordered motions, and gas velocity dispersion $\sigma_g$, which quantify disordered motions, are adopted from the DEEP2 and SIGMA surveys. This sample covers a continuous baseline in redshift from $z=2.5$ to $z=0.1$, spanning 10 Gyrs. At low redshift, nearly all sufficiently massive star-forming galaxies are rotationally supported ($V_{rot}>\sigma_g$). By $z=2$, the percentage of galaxies with rotational support has declined to 50$\%$ at low stellar mass ($10^{9}-10^{10}\,M_{\odot}$) and 70$\%$ at high stellar mass ($10^{10}-10^{11}M_{\odot}$). For $V_{rot}\,>\,3\,\sigma_g$, the percentage drops below 35$\%$ for all masses. From $z\,=\,2$ to now, galaxies exhibit remarkably smooth kinematic evolution on average. All galaxies tend towards rotational support with time, and it is reached earlier in higher mass systems. This is mostly due to an average decline in $\sigma_g$ by a factor of 3 since a redshift of 2, which is independent of mass. Over the same time period, $V_{rot}$ increases by a factor of 1.5 for low mass systems, but does not evolve for high mass systems. These trends in $V_{rot}$ and $\sigma_g$ with time are at a fixed stellar mass and should not be interpreted as evolutionary tracks for galaxy populations. When galaxy populations are linked in time with abundance matching, not only does $\sigma_g$ decline with time as before, but $V_{rot}$ strongly increases with time for all galaxy masses. This enhances the evolution in $V_{rot}/\sigma_g$. These results indicate that $z\,=\,2$ is a period of disk assembly, during which the strong rotational support present in today's massive disk galaxies is only just beginning to emerge.Comment: 12 pages, 8 figures, submitted to Ap